Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.64 |
| ▸ | ACACA | Q13085 | 1/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14936498 | 1.00 | ACACB (0.64) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL21548177 | 0.92 | ACACB (0.65) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14944971 | 0.91 | ACACB (0.66) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL29538711 | 0.90 | ACACB (0.76) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936098 | 0.90 | ACACB (0.76) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936324 | 0.90 | ACACB (0.62) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL29538642 | 0.89 | ACACB (0.64) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936501 | 0.89 | ACACB (0.64) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936400 | 0.89 | ACACB (0.64) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL29453870 | 0.89 | ACACB (0.64) | ACACBACACAADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970760-B | ACC inhibitors and uses thereof | 吉利德阿波罗公司 | 2022-04-26 | — | — | CN | disclosed |
| EP-3628320-B1 | ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO LLC (US) | 2022-03-16 | — | — | EP | disclosed |