SCHEMBL29454374

SCHEMBL29454374

COc1ccc(/C=C/C(=O)CC(=O)/C=C/c2cccc(O)c2OC)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 14/20 1.00
MAPT P10636 5/20 1.00
MEN1 O00255 2/20 1.00
ALDH1A1 P00352 2/20 1.00
THRB P10828 2/20 1.00
KMT2A Q03164 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
APP P05067 4/20 0.83
NFE2L2 Q16236 3/20 0.62
CYP2D6 P10635 2/20 0.59
CYP2C9 P11712 2/20 0.59
TSHR P16473 2/20 0.59
HSD17B10 Q99714 2/20 0.59
CYP2C19 P33261 1/20 0.59
KDM4E B2RXH2 1/20 0.59
PTGES O14684 1/20 0.59
HDAC3 O15379 1/20 0.59
CA12 O43570 1/20 0.59
DYRK3 O43781 1/20 0.59
PLIN1 O60240 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3208503 1.00 BACE1 (1.00) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3208488 1.00 BACE1 (1.00) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3200444 0.93 BACE1 (0.87) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3200464 0.93 BACE1 (0.87) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3211161 0.91 MAPT (1.00) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3211174 0.91 MAPT (1.00) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3218229 0.90 BACE1 (0.82) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3218266 0.90 BACE1 (0.82) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3209685 0.89 BACE1 (0.80) BACE1MAPTMEN1ALDH1A1THRB
SCHEMBL3209671 0.89 BACE1 (0.80) BACE1MAPTMEN1ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11811506-B2 Application of key exchange based physical layer security methods ISTANBUL TEKNIK UNIVERSITESI (TR) 2023-11-07 US disclosed
US-20220094460-A1 APPLICATION OF KEY EXCHANGE BASED PHYSICAL LAYER SECURITY METHODS ISTANBUL TEKNIK UNIVERSITESI (TR) 2022-03-24 US disclosed