Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945677 | 0.83 | ALK (0.66) | ALKINSR | |
| SCHEMBL886544 | 0.82 | ALK (0.74) | ALKINSR | |
| SCHEMBL2061470 | 0.76 | ALK (0.58) | ALKINSR | |
| SCHEMBL885931 | 0.76 | ALK (0.75) | ALKINSR | |
| SCHEMBL885973 | 0.76 | ALK (0.68) | ALKINSR | |
| SCHEMBL2938625 | 0.76 | ALK (0.66) | ALKINSR | |
| SCHEMBL885796 | 0.76 | ALK (0.66) | ALKINSR | |
| SCHEMBL885789 | 0.75 | ALK (0.84) | ALKINSR | |
| SCHEMBL886007 | 0.75 | ALK (0.70) | ALKINSR | |
| SCHEMBL885884 | 0.75 | ALK (0.82) | ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |