Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 15/20 | 0.62 |
| ▸ | MAPK7 | Q13164 | 5/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.58 |
| ▸ | GAK | O14976 | 1/20 | 0.58 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.58 |
| ▸ | DCLK2 | Q8N568 | 1/20 | 0.58 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.57 |
| ▸ | TTK | P33981 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458512 | 0.88 | MAPK7 (0.56) | TNK2MAPK7LRRK2DCLK1TTK | |
| SCHEMBL24495977 | 0.86 | TNK2 (0.61) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL29458704 | 0.81 | TNK2 (0.61) | TNK2 | |
| SCHEMBL27196794 | 0.81 | MAPK7 (0.63) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL29714307 | 0.81 | MAPK7 (0.63) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL24496118 | 0.80 | MAPK7 (0.68) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL10098756 | 0.79 | TNK2 (0.71) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL616987 | 0.78 | TNK2 (0.75) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL27196830 | 0.78 | MAPK7 (0.59) | TNK2MAPK7LRRK2GAKDCLK1 | |
| SCHEMBL29573093 | 0.77 | TNK2 (0.59) | TNK2MAPK7LRRK2GAKDCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109836427-B | Pyrimidopyrimidinone compounds and application thereof | 暨南大学 | 2022-04-15 | — | — | CN | disclosed |