SCHEMBL29459481

SCHEMBL29459481

CC1CC(C)(C)CC(c2ccc(O)c(C(C)(C)C)c2)(c2ccc(O)c(C(C)(C)C)c2)C1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ESR2 Q92731 4/20 0.60
ALDH1A1 P00352 6/20 0.40
ALOX15 P16050 4/20 0.40
LMNA P02545 2/20 0.40
NR1I2 O75469 1/20 0.40
CYP2C9 P11712 1/20 0.40
MIF P14174 1/20 0.40
TYR P14679 1/20 0.40
HTT P42858 1/20 0.40
NFE2L2 Q16236 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPT P10636 1/20 0.38
ATP2A2 P16615 1/20 0.38
ATP2A3 Q93084 1/20 0.38
ATM Q13315 1/20 0.34
HSP90AA1 P07900 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297457 1.00 ESR1 (0.60) ESR1ESR2ALDH1A1ALOX15LMNA
SCHEMBL6258466 0.91 ESR1 (0.50) ESR1ESR2ALDH1A1ALOX15LMNA
SCHEMBL7653011 0.89 ESR1 (0.48) ESR1ESR2ALDH1A1ALOX15LMNA
SCHEMBL297281 0.84 ESR1 (0.56) ESR1ESR2ALDH1A1ALOX15LMNA
SCHEMBL21538491 0.84 ESR1 (0.69) ESR1ESR2ALDH1A1LMNACYP2C9
SCHEMBL244496 0.81 ESR1 (0.65) ESR1ESR2ALDH1A1LMNACYP2C9
SCHEMBL29459501 0.81 ESR1 (0.65) ESR1ESR2ALDH1A1LMNACYP2C9
SCHEMBL29404012 0.81 ESR1 (0.65) ESR1ESR2ALDH1A1LMNACYP2C9
SCHEMBL296382 0.80 ESR1 (0.63) ESR1ESR2ALDH1A1ALOX15TSHR
SCHEMBL7909628 0.80 ESR1 (0.63) ESR1ESR2CYP2C9CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022075328-A1 POLYCARBONATE RESIN COMPOSITION AND CIRCUIT MOLDED ARTICLE FOR COMMUNICATION DEVICES 帝人株式会社 2022-04-14 WO disclosed