Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24337574 | 1.00 | NR1H2 (0.40) | NR1H2USP2SMN1; SMN2PIK3CDCHRM2 | |
| SCHEMBL5508969 | 0.92 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2PIK3CDCHRM2 | |
| SCHEMBL2436796 | 0.92 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2PIK3CDCHRM2 | |
| SCHEMBL342821 | 0.92 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2PIK3CDCHRM2 | |
| SCHEMBL25313625 | 0.84 | MGAM (0.30) | — | |
| SCHEMBL25313629 | 0.84 | MGAM (0.30) | — | |
| SCHEMBL19420219 | 0.83 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL2441060 | 0.83 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL30287755 | 0.83 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL2441058 | 0.83 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365589-A1 | NOVEL AMINE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2023-11-16 | — | — | US | disclosed |
| EP-4215534-A1 | AMINE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-26 | — | — | EP | disclosed |
| CN-116209441-A | Novel amine derivatives | 住友制药株式会社 | 2023-06-02 | — | — | CN | disclosed |
| WO-2022059779-A1 | AMINE DERIVATIVE | 大日本住友製薬株式会社 | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365589-A1 | NOVEL AMINE DERIVATIVES | DYRK2, DYRK1A, DYRK1B | NR1H2 2623/4885USP2 3942/4885SMN1; SMN2 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.