Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462780 | 0.90 | HDAC11 (0.65) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30016167 | 0.89 | HDAC11 (0.66) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30015185 | 0.89 | HDAC11 (0.77) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30016430 | 0.89 | HDAC11 (0.66) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL23005165 | 0.86 | HDAC11 (0.61) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL23005164 | 0.86 | HDAC11 (0.61) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30015358 | 0.86 | HDAC11 (0.57) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL15232872 | 0.85 | HDAC11 (0.52) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL2487519 | 0.85 | HDAC11 (0.52) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL23005221 | 0.83 | HDAC11 (0.58) | HDAC11HDAC2HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022229017-A1 | ADAMANTYL RETINOID DERIVATIVE WITH ANTICANCER ACTIVITY | BIOGEM S.C.A R.L. (IT) | 2022-11-03 | — | — | WO | claimed |
| WO-2022229017-A1 | ADAMANTYL RETINOID DERIVATIVE WITH ANTICANCER ACTIVITY | BIOGEM S.C.A R.L. (IT) | 2022-11-03 | — | — | WO | disclosed |
| CN-110114338-B | Retinoid derivatives having antitumor activity | 比奥吉公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-3962887-A1 | PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE | Special Product's Line S.p.A. (IT) | 2022-03-09 | — | — | EP | disclosed |