Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694873 | 0.84 | TTK (0.50) | TTKCLK1CLK2PIK3CBMAPK8 | |
| SCHEMBL3711102 | 0.83 | TTK (0.51) | TTKCLK1CLK2PIK3CBMAPK8 | |
| SCHEMBL3699681 | 0.82 | TTK (0.50) | TTKCLK1CLK2PIK3CBMAPK8 | |
| SCHEMBL4766150 | 0.81 | TTK (0.54) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3040661 | 0.81 | TTK (0.53) | TTKCLK1CLK2PIK3CBMAPK8 | |
| SCHEMBL4766022 | 0.81 | TTK (0.52) | TTKCLK1CLK2PIK3CBMAPK8 | |
| SCHEMBL3707025 | 0.79 | TTK (0.55) | TTKPIK3CBMAPK8PTK2CCNA2 | |
| SCHEMBL3253947 | 0.78 | TTK (0.68) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3260718 | 0.78 | TTK (0.50) | TTKPIK3CBMAPK8PTK2CCNA2 | |
| SCHEMBL2948829 | 0.77 | TTK (0.55) | TTKPIK3CBMAPK8PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |