Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25253735 | 1.00 | TTR (0.52) | TTRMAPK1HSD17B10KDM4ELMNA | |
| SCHEMBL29463780 | 0.95 | TTR (0.56) | TTRHSD17B10KDM4ELMNASMN1; SMN2 | |
| SCHEMBL25292206 | 0.95 | TTR (0.56) | TTRHSD17B10KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6672350 | 0.92 | TTR (0.60) | TTRMAPK1HSD17B10KDM4ELMNA | |
| SCHEMBL11093699 | 0.90 | TTR (0.59) | TTRMAPK1HSD17B10KDM4ELMNA | |
| Phosphine SCHEMBL4434544 | 0.90 | TTR (0.59) | TTRMAPK1HSD17B10KDM4ELMNA | |
| SCHEMBL30493137 | 0.88 | MEN1 (0.56) | MAPK1HSD17B10KDM4ELMNAHTT | |
| SCHEMBL25248791 | 0.88 | MEN1 (0.56) | MAPK1HSD17B10KDM4ELMNAHTT | |
| SCHEMBL5387584 | 0.86 | TTR (0.65) | TTRHSD17B10KDM4ELMNASMN1; SMN2 | |
| SCHEMBL2074825 | 0.82 | SLC2A1 (0.52) | TTRMAPK1HSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390572-A | Dichloroacetic acid coupling diphenyl ethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114230466-B | Dichloroacetic acid coupling diphenyl ethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2023123695-A1 | DICHLOROACETIC-ACID-COUPLED DIPHENYLETHANE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华理生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-114230466-A | Dichloroacetic acid coupled diphenylethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2022-03-25 | — | — | CN | disclosed |