Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.34 |
| ▸ | HTR2B | P41595 | 7/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.32 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464547 | 1.00 | HTR2C (0.34) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL19925202 | 1.00 | HTR2C (0.34) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL29464957 | 1.00 | HTR2C (0.34) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL19927715 | 1.00 | HTR2C (0.34) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL29464512 | 0.90 | HTR2C (0.40) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL19951341 | 0.90 | HTR2C (0.40) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL29464303 | 0.90 | HTR2C (0.40) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL19951343 | 0.90 | HTR2C (0.40) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| SCHEMBL19968833 | 0.90 | HTR2C (0.40) | HTR2CHTR2BHTR2ASCN9ASCN1A | |
| Hydrochloric Acid SCHEMBL19951372 | 0.89 | HTR2C (0.40) | HTR2CHTR2BHTR2ASCN9ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |