Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.39 |
| ▸ | SCN1A | P35498 | 6/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23651319 | 1.00 | IRAK4 (0.39) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| SCHEMBL19951379 | 1.00 | IRAK4 (0.39) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| SCHEMBL19951378 | 1.00 | IRAK4 (0.39) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| SCHEMBL29464496 | 1.00 | IRAK4 (0.39) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| SCHEMBL19927708 | 1.00 | IRAK4 (0.39) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| Hydrochloric Acid SCHEMBL19927738 | 0.99 | IRAK4 (0.38) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| Hydrochloric Acid SCHEMBL29464904 | 0.99 | IRAK4 (0.38) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| Hydrochloric Acid SCHEMBL19951321 | 0.99 | IRAK4 (0.38) | IRAK4SCN1ASCN8AGRM2SCN5A | |
| SCHEMBL19925114 | 0.84 | SCN1A (0.35) | IRAK4SCN1ASCN8ASCN5AGHSR | |
| SCHEMBL29464445 | 0.84 | SCN1A (0.35) | IRAK4SCN1ASCN8ASCN5AGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |