Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925737 | 1.00 | SCN1A (0.32) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19925736 | 1.00 | SCN1A (0.32) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19925190 | 0.94 | TAAR1 (0.34) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19925192 | 0.94 | TAAR1 (0.34) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19925824 | 0.91 | SCN1A (0.32) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19925823 | 0.91 | SCN1A (0.32) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19951401 | 0.89 | SCN9A (0.33) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19925421 | 0.89 | SCN9A (0.33) | SCN1ASCN8ASCN9ATTREIF2AK4 | |
| SCHEMBL19927721 | 0.88 | SCN9A (0.32) | SCN1ASCN8ASCN9AEIF2AK4BTK | |
| SCHEMBL19951451 | 0.88 | SCN9A (0.32) | SCN1ASCN8ASCN9AEIF2AK4BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |