Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 11/20 | 0.41 |
| ▸ | FAP | Q12884 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38659787 | 0.90 | XIAP (0.51) | XIAPDPP4FAPDPP8DPP9 | |
| SCHEMBL30051887 | 0.87 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL20250609 | 0.84 | XIAP (0.58) | XIAPDPP4FAPDPP8DPP9 | |
| SCHEMBL30051223 | 0.84 | XIAP (0.58) | XIAPDPP4FAPDPP8DPP9 | |
| SCHEMBL30226106 | 0.84 | DPP4 (0.42) | XIAPDPP4FAPDPP8DPP9 | |
| SCHEMBL38658690 | 0.84 | ACE (0.44) | XIAPDPP4FAPDPP8DPP9 | |
| SCHEMBL30138994 | 0.83 | XIAP (0.43) | XIAPDPP4FAPDPP8DPP9 | |
| SCHEMBL30997469 | 0.82 | XIAP (0.45) | XIAPDPP4FAPPREP | |
| SCHEMBL18639824 | 0.82 | PREP (0.44) | XIAPDPP4FAPPREPACE | |
| SCHEMBL30853261 | 0.82 | ACE (0.42) | XIAPDPP4FAPPREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876578-B | Amphiphilic glucan derivative carrier targeting tumor-associated fibroblasts, and preparation and application of pharmaceutical composition of amphiphilic glucan derivative carrier | 中国药科大学 | 2022-03-18 | — | — | CN | claimed |
| CN-112876578-B | Amphiphilic glucan derivative carrier targeting tumor-associated fibroblasts, and preparation and application of pharmaceutical composition of amphiphilic glucan derivative carrier | 中国药科大学 | 2022-03-18 | — | — | CN | disclosed |