SCHEMBL29465233

SCHEMBL29465233

O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.65
P2RY1 P47900 4/20 0.59
ENPP1 P22413 3/20 0.59
P2RX3 P56373 4/20 0.56
P2RX1 P51575 3/20 0.56
P2RX2 Q9UBL9 3/20 0.56
DTYMK P23919 2/20 0.54
P2RY2 P41231 2/20 0.53
P2RX4 Q99571 2/20 0.53
SRC P12931 1/20 0.53
ALDH1A1 P00352 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
GPR17 Q13304 1/20 0.53
RNASEL Q05823 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1763078 1.00 POLB (0.65) POLBP2RY1ENPP1P2RX3P2RX1
SCHEMBL245486 1.00 POLB (0.65) POLBP2RY1ENPP1P2RX3P2RX1
SCHEMBL2508660 0.99 POLB (0.66) POLBP2RY1ENPP1P2RX3P2RX1
SCHEMBL2508646 0.99 POLB (0.66) POLBP2RY1ENPP1P2RX3P2RX1
SCHEMBL1533826 0.91 POLB (0.65) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL1533828 0.91 POLB (0.65) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL20266303 0.90 POLB (0.64) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL12943893 0.90 POLB (0.62) POLBP2RY1ENPP1P2RX3P2RX1
SCHEMBL12932282 0.90 POLB (0.64) POLBP2RY1ENPP1P2RX3P2RX1
SCHEMBL14471000 0.90 POLB (0.80) POLBP2RY1ENPP1P2RX3P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN disclosed
CN-119948168-A Method and apparatus for measuring duplex unwinding or strand exchange efficiency 瑞孚迪健康科学有限公司 2025-05-06 CN disclosed
CN-118591639-A Method for detecting target nucleic acid point mutation through loop-mediated isothermal amplification 南洋理工大学 2024-09-03 CN disclosed
CN-113736858-B Real-time monitoring method for nucleic acid amplicon mediated by cyclic oligonucleotide probe 香港科技大学 2024-05-10 CN disclosed
CN-117795096-A Methods, compositions and kits for preparing sequencing libraries 吉复生物科技有限公司 2024-03-29 CN disclosed
EP-3313992-B1 SELECTIVE DEGRADATION OF WILD-TYPE DNA AND ENRICHMENT OF MUTANT ALLELES USING NUCLEASE DANA FARBER CANCER INST INC (US) 2022-03-23 EP disclosed
EP-3963102-A1 UTILIZATION OF DITP FOR PREFERENTIAL/SELECTIVE AMPLIFICATION OF RNA VERSUS DNA TARGETS BASED ON STRAND-SEPARATION TEMPERATURE F. Hoffmann-La Roche AG (CH) 2022-03-09 EP disclosed