⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410768 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9551867 | 0.62 | — | — | |
| Carbon Monoxide SCHEMBL4947656 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL4157813 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL1993779 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL359598 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL8004075 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL337054 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL3353062 | 0.61 | — | — | |
| Carbon Monoxide SCHEMBL6139548 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785616-B2 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2010-08-31 | — | — | US | disclosed |
| US-20070258942-A1 | C-Nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
| US-7259250-B2 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1330425-B1 | C-NITROSO COMPOUNDS AND USE THEREOF | UNIV DUKE (US) | 2007-06-13 | — | — | EP | disclosed |
| US-7049308-B2 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2006-05-23 | — | — | US | disclosed |
| US-7030238-B2 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20050203295-A1 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2005-09-15 | — | — | US | disclosed |
| US-20050187166-A1 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2005-08-25 | — | — | US | disclosed |
| US-6887994-B2 | Such as dimeric 2-(4'-(alpha-nitroso)isobutyrylphenyl) propionic acid formed by nitrosylation of carbon acid; useful as nitrogen oxide donor; for treating pain/inflammation | DUKE UNIVERSITY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040006059-A1 | C-nitroso compounds and use thereof | DUKE UNIVERSITY | 2004-01-08 | — | — | US | disclosed |
| US-20030176668-A1 | C-nitroso compounds and use thereof | STAMLER JONATHAN S (US) | 2003-09-18 | — | — | US | disclosed |
| EP-1330425-A2 | C-NITROSO COMPOUNDS AND USE THEREOF | DUKE UNIVERSITY (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6538116-B2 | For therapy of inflammatory or painful disorder | DUKE UNIVERSITY | 2003-03-25 | — | — | US | disclosed |
| US-20020077506-A1 | For therapy of inflammatory or painful disorder | STAMLER JONATHAN S (US) | 2002-06-20 | — | — | US | disclosed |
| WO-2002034705-A2 | C-NITROSO COMPOUNDS AND USE THEREOF | DUKE UNIVERSITY (US) | 2002-05-02 | — | — | WO | disclosed |
| US-6359182-B1 | VASCULAR SYSTEM RELAXATION; ANTIINFLAMMATORY AGENTS; ANALGESICS | DUKE UNIVERSITY | 2002-03-19 | — | — | US | disclosed |