Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22772892 | 1.00 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL22772824 | 0.88 | GRIN2B (0.79) | GRIN2BGRIN1 | |
| SCHEMBL29465728 | 0.88 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL22772842 | 0.88 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL22772825 | 0.87 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL29465736 | 0.87 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL22787202 | 0.85 | GRIN2B (0.78) | GRIN2BGRIN1 | |
| SCHEMBL22772883 | 0.83 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL22775088 | 0.83 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL29525257 | 0.83 | GRIN2B (1.00) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983413-A1 | SUBSTITUTED PYRAZOLO-PYRAZINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | claimed |
| EP-3983413-A1 | SUBSTITUTED PYRAZOLO-PYRAZINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |