Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.80 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 7/20 | 0.45 |
| ▸ | ATR | Q13535 | 2/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311793 | 1.00 | LANCL2 (0.80) | LANCL2PIM1PARP1PARP2MEN1 | |
| SCHEMBL29063415 | 0.91 | LANCL2 (0.84) | LANCL2MEN1KMT2AHSD11B1HTR2B | |
| Omilancor SCHEMBL17706588 | 0.90 | LANCL2 (1.00) | LANCL2MEN1KMT2AHSD11B1HTR2B | |
| Omilancor SCHEMBL29349469 | 0.90 | LANCL2 (1.00) | LANCL2MEN1KMT2AHSD11B1HTR2B | |
| SCHEMBL29484591 | 0.87 | LANCL2 (0.77) | LANCL2HTR2B | |
| SCHEMBL25310510 | 0.87 | LANCL2 (0.77) | LANCL2HTR2B | |
| SCHEMBL18805072 | 0.86 | LANCL2 (0.88) | LANCL2MEN1KMT2AHTR2BATR | |
| SCHEMBL21043129 | 0.86 | LANCL2 (0.93) | LANCL2MEN1KMT2AHSD11B1HTR2B | |
| SCHEMBL17705594 | 0.86 | LANCL2 (0.88) | LANCL2PARP1MEN1KMT2AHSD11B1 | |
| SCHEMBL25312485 | 0.85 | LANCL2 (0.74) | LANCL2MEN1KMT2AHSD11B1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195780-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195806-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |