Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.72 |
| ▸ | JAK2 | O60674 | 12/20 | 0.72 |
| ▸ | TYK2 | P29597 | 10/20 | 0.71 |
| ▸ | JAK3 | P52333 | 6/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22638013 | 1.00 | JAK1 (0.72) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL29467012 | 1.00 | JAK1 (0.72) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22638037 | 0.96 | JAK1 (0.76) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL29467004 | 0.96 | JAK1 (0.76) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22638016 | 0.90 | JAK1 (0.75) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL29467007 | 0.90 | JAK1 (0.75) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL29467006 | 0.90 | JAK1 (0.75) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648683 | 0.90 | JAK1 (0.65) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL28722824 | 0.89 | JAK1 (0.61) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648717 | 0.88 | JAK1 (0.72) | JAK1JAK2TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966209-A1 | JAK INHIBITORS | Vimalan Biosciences, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |