SCHEMBL29467237

SCHEMBL29467237

Oc1cccc(F)c1-c1c(O)ccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
MAPT P10636 5/20 0.49
KDM4E B2RXH2 3/20 0.49
MAPK1 P28482 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
NPC1 O15118 1/20 0.49
PTPN22 Q9Y2R2 1/20 0.48
POLB P06746 1/20 0.46
HSD17B10 Q99714 2/20 0.44
USP2 O75604 1/20 0.44
PAK1 Q13153 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NSD2 O96028 1/20 0.43
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43
HKDC1 Q2TB90 1/20 0.43
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23581959 1.00 CYP1A2 (0.52) CYP1A2MAPTKDM4EMAPK1L3MBTL1
SCHEMBL29216526 0.89 PTPN22 (0.52) CYP1A2MAPTKDM4EMAPK1L3MBTL1
SCHEMBL24758933 0.86 CYP1A2 (0.46) CYP1A2MAPTKDM4EMAPK1L3MBTL1
SCHEMBL22541875 0.86 CYP1A2 (0.62) CYP1A2MAPTKDM4EL3MBTL1PTPN22
1-Naphthol SCHEMBL5492646 0.84 CYP1A2 (0.74) CYP1A2MAPTKDM4EPTPN22POLB
SCHEMBL29027 0.84 PTPN22 (0.65) CYP1A2MAPTKDM4EPTPN22POLB
SCHEMBL29362162 0.84 PTPN22 (0.65) CYP1A2MAPTKDM4EPTPN22POLB
SCHEMBL15400598 0.84 PTPN22 (0.65) CYP1A2MAPTKDM4EPTPN22POLB
Methane SCHEMBL10406101 0.82 PTPN22 (0.62) CYP1A2MAPTKDM4EL3MBTL1PTPN22
Water SCHEMBL18660620 0.82 PTPN22 (0.62) CYP1A2MAPTKDM4EPTPN22POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114207862-A Organic electroluminescent element, composition, powder, electronic device, and novel compound 出光兴产株式会社 2022-03-18 CN disclosed