Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660247 | 1.00 | AGPAT2 (0.57) | AGPAT2MAPTNPSR1CASP3SENP7 | |
| SCHEMBL29469501 | 0.91 | AGPAT2 (0.47) | AGPAT2MAPTNPSR1NPC1RAB9A | |
| SCHEMBL22660230 | 0.91 | AGPAT2 (0.47) | AGPAT2MAPTNPSR1NPC1RAB9A | |
| SCHEMBL29783280 | 0.89 | MAPT (0.48) | AGPAT2MAPTNPC1RAB9APOLB | |
| SCHEMBL22674259 | 0.89 | AGPAT2 (0.53) | AGPAT2MAPTNPSR1CASP3SENP7 | |
| SCHEMBL22660268 | 0.89 | MAPT (0.48) | AGPAT2MAPTNPC1RAB9APOLB | |
| SCHEMBL29783182 | 0.89 | AGPAT2 (0.53) | AGPAT2MAPTNPSR1CASP3SENP7 | |
| SCHEMBL22660259 | 0.87 | AGPAT2 (0.56) | AGPAT2MAPTNPC1RAB9APOLB | |
| SCHEMBL29469486 | 0.87 | AGPAT2 (0.56) | AGPAT2MAPTNPC1RAB9APOLB | |
| SCHEMBL29469493 | 0.87 | AGPAT2 (0.56) | AGPAT2MAPTNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206443-B | Aromatic or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114206443-A | Aromatic ring or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |