Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855816 | 1.00 | KMT2A (0.57) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL3529089 | 0.90 | EDNRA (0.53) | KMT2ARXFP1EDNRAALDH1A1KDM4E | |
| SCHEMBL15461560 | 0.85 | KMT2A (0.59) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL1857055 | 0.85 | KMT2A (0.59) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8861874 | 0.84 | KMT2A (0.57) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL4115318 | 0.84 | KMT2A (0.57) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL4115316 | 0.83 | KMT2A (0.56) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL31689448 | 0.83 | KMT2A (0.56) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL2371826 | 0.81 | KMT2A (0.58) | KMT2ARXFP1CCR8EDNRAALDH1A1 | |
| SCHEMBL1338666 | 0.81 | CCR8 (0.68) | CCR8HPGDEPHX1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |