Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777856 | 0.99 | MME (0.39) | MMETGFBR1SLC15A2BACE1AKR1B1 | |
| SCHEMBL29630315 | 0.98 | MME (0.36) | MMESLC15A2 | |
| SCHEMBL29590288 | 0.98 | MME (0.36) | MMESLC15A2 | |
| SCHEMBL29630312 | 0.95 | MME (0.34) | MMESLC15A2CPB2 | |
| SCHEMBL30272502 | 0.95 | MME (0.34) | MMESLC15A2CPB2 | |
| SCHEMBL38661411 | 0.94 | MME (0.39) | MMETGFBR1SLC15A2BACE1AKR1B1 | |
| SCHEMBL30253800 | 0.94 | MME (0.39) | MMETGFBR1SLC15A2BACE1AKR1B1 | |
| SCHEMBL30559586 | 0.93 | MME (0.36) | MMECPB2 | |
| SCHEMBL2132240 | 0.93 | MME (0.36) | MMECPB2 | |
| SCHEMBL2132230 | 0.93 | MME (0.36) | MMECPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688175-B1 | GENETICALLY MODIFIED ISOPROPYLMALATE ISOMERASE ENZYME COMPLEXES AND PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C5-C10 COMPOUNDS THEREWITH | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11898181-B2 | Genetically modified isopropylmalate isomerase enzyme complexes and processes to prepare elongated 2-ketoacids and C5-C10 compounds therewith | DOW GLOBAL TECHNOLOGIES LLC | 2024-02-13 | — | — | US | disclosed |
| US-20220098567-A1 | GENETICALLY MODIFIED ISOPROPYLMALATE ISOMERASE ENZYME COMPLEXES AND PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C5-C10 COMPOUNDS THEREWITH | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-03-31 | — | — | US | disclosed |