Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947515 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2944268 | 0.99 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2944269 | 0.99 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL2945727 | 0.91 | F10 (0.43) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL2945729 | 0.91 | F10 (0.43) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL4316217 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL4316221 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL13744665 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2941144 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2941139 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489078-B1 | BENZOFURAN DERIVATIVE | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-01-06 | — | — | EP | disclosed |