Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.32 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25318324 | 1.00 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL29475564 | 1.00 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL25320430 | 1.00 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL25322131 | 1.00 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL30476673 | 1.00 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL25317544 | 0.85 | ERN1 (0.47) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL29475606 | 0.85 | ERN1 (0.47) | ERN1KMT2AKDM4ENPC1TSHR | |
| SCHEMBL29475543 | 0.85 | ERN1 (0.40) | ERN1ALDH1A1HPGDLMNA | |
| SCHEMBL25319769 | 0.85 | ERN1 (0.40) | ERN1ALDH1A1HPGDLMNA | |
| SCHEMBL25319039 | 0.84 | NPC1 (0.45) | ERN1NPC1RAB9AMBTD1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217342-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022067114-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2022-03-31 | — | — | WO | disclosed |