SCHEMBL29475845

SCHEMBL29475845

[3H]c1cc2c([nH]c3nc(-c4ccc(F)nc4[3H])ccc32)c([3H])n1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475838 0.90 MAPT (0.52) MAPT
SCHEMBL29475836 0.81 MAPT (0.68) MAPT
SCHEMBL29475855 0.72 MAPT (0.67) MAPT
SCHEMBL17967548 0.71 MAPT (1.00) MAPT
SCHEMBL29475826 0.70 MAPT (0.62) MAPT
SCHEMBL16634186 0.68 MAPT (0.81) MAPT
SCHEMBL29598856 0.68 MAPT (0.81) MAPT
SCHEMBL17975131 0.68 MAPT (0.81) MAPT
SCHEMBL29475839 0.67 MAPT (0.55) MAPT
SCHEMBL29475831 0.67 MAPT (0.52) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12006316-B2 9H-pyrrolo-dipyridine derivatives UCB Biopharma SRL (BE) 2024-06-11 US disclosed
US-20220213103-A1 9H-PYRROLO-DIPYRIDINE DERIVATIVES UCB Biopharma SRL (BE) 2022-07-07 US disclosed
US-11312716-B2 9H-pyrrolo-dipyridine derivatives UCB Biopharma SRL 2022-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213103-A1 9H-PYRROLO-DIPYRIDINE DERIVATIVES MAPT, PSEN1, PRNP MAPT 1/4885
US-12006316-B2 9H-pyrrolo-dipyridine derivatives MAPT, PSEN1, PRNP MAPT 1/4885
US-11312716-B2 9H-pyrrolo-dipyridine derivatives MAPT, PSEN1, PRNP MAPT 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.