Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460689 | 0.95 | FOLH1 (0.49) | FOLH1DPP8DPP9DPP4BACE1 | |
| SCHEMBL28081108 | 0.94 | BACE1 (0.48) | FOLH1BACE1CTSDBACE2 | |
| SCHEMBL31031475 | 0.93 | FOLH1 (0.47) | FOLH1DPP8DPP9DPP4BACE1 | |
| SCHEMBL38657332 | 0.92 | GSR (0.46) | DPP8DPP9NMT2NMT1FURIN | |
| SCHEMBL30932140 | 0.92 | FOLH1 (0.49) | FOLH1NMT2NMT1FURINPDCD1LG2 | |
| SCHEMBL29736457 | 0.90 | FOLH1 (0.56) | FOLH1DPP8DPP9DPP4BACE1 | |
| SCHEMBL30924861 | 0.90 | DPP4 (0.52) | DPP8DPP9DPP4BACE1CTSD | |
| SCHEMBL30361178 | 0.90 | DPP4 (0.52) | DPP8DPP9DPP4BACE1CTSD | |
| SCHEMBL31257236 | 0.90 | BACE1 (0.47) | FOLH1BACE1CTSDBACE2 | |
| SCHEMBL29571467 | 0.89 | BACE1 (0.46) | FOLH1BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312390-B2 | Rapid-acting insulin analogues of enhanced stability | CASE WESTERN RESERVE UNIVERSITY (US) | 2025-05-27 | — | — | US | disclosed |
| WO-2022136555-A9 | IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2022-09-22 | — | — | WO | disclosed |
| US-11332735-B2 | Method of improving characteristics of proteins | FULL SPECTRUM GENETICS, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20220112262-A1 | RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY | CASE WESTERN RESERVE UNIVERSITY | 2022-04-14 | — | — | US | disclosed |
| EP-3958886-A1 | COMPOSITIONS AND METHODS FOR PROTECTING EPITHELIAL AND BARRIER INTEGRITY | Ocunexus Therapeutics, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |