SCHEMBL29477259

SCHEMBL29477259

CCOc1ccc(-c2nc(-c3ccncc3)no2)cc1OCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 15/20 1.00
S1PR3 Q99500 10/20 1.00
MAPT P10636 4/20 1.00
HSD17B10 Q99714 3/20 0.90
ALDH1A1 P00352 2/20 0.90
HPGD P15428 2/20 0.90
KDM4E B2RXH2 2/20 0.78
NPC1 O15118 2/20 0.78
RAB9A P51151 1/20 0.78
LMNA P02545 1/20 0.74
SMN1; SMN2 Q16637 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13417065 1.00 S1PR1 (1.00) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL1413267 0.95 S1PR1 (1.00) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL13417216 0.94 S1PR1 (1.00) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL20615557 0.92 S1PR1 (1.00) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL19766693 0.88 S1PR1 (0.91) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL13525818 0.88 S1PR1 (0.79) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL13416527 0.88 HSD17B10 (1.00) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL14327929 0.88 HSD17B10 (0.80) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL566785 0.88 HSD17B10 (0.80) S1PR1S1PR3MAPTHSD17B10ALDH1A1
SCHEMBL13525126 0.86 S1PR1 (0.76) S1PR1S1PR3MAPTHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11600045-B2 Collaborative light show authoring for tessellated geometries CONTRAVENTUM, LLC (US) 2023-03-07 US disclosed
US-20220366648-A1 Collaborative Light Show Authoring for Tessellated Geometries CONTRAVENTUM, LLC (US) 2022-11-17 US disclosed
CN-112972394-B Curcumin solid dispersion and mechanical force preparation method thereof 浙江工业大学 2022-09-13 CN disclosed
US-11282276-B2 Collaborative light show authoring for tessellated geometries CONTRAVENTUM, LLC (US) 2022-03-22 US disclosed