SCHEMBL29478372

SCHEMBL29478372

N#Cc1cccc(C[C@H](N)CC(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.60
DPP4 P27487 2/20 0.60
FOLH1 Q04609 1/20 0.53
PIN1 Q13526 1/20 0.53
FFAR1 O14842 3/20 0.48
FAP Q12884 1/20 0.48
DPP8 Q6V1X1 1/20 0.48
DPP9 Q86TI2 1/20 0.48
MMP12 P39900 1/20 0.48
MMP13 P45452 1/20 0.48
FFAR4 Q5NUL3 1/20 0.47
EPHX1 P07099 1/20 0.46
MME P08473 1/20 0.46
LMNA P02545 1/20 0.45
MAOB P27338 1/20 0.45
ANPEP P15144 1/20 0.44
ENPEP Q07075 1/20 0.44
GLA P06280 1/20 0.44
MEP1A Q16819 1/20 0.44
MEP1B Q16820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2035561 1.00 DPP7 (0.60) DPP7DPP4FOLH1PIN1FFAR1
SCHEMBL2030772 1.00 DPP7 (0.60) DPP7DPP4FOLH1PIN1FFAR1
SCHEMBL29478390 1.00 DPP7 (0.60) DPP7DPP4FOLH1PIN1FFAR1
SCHEMBL2030774 1.00 DPP7 (0.60) DPP7DPP4FOLH1PIN1FFAR1
SCHEMBL29557415 0.82 FOLH1 (0.59) DPP7DPP4FOLH1FAPDPP8
SCHEMBL29397955 0.82 FOLH1 (0.59) DPP7DPP4FOLH1FAPDPP8
SCHEMBL43811 0.82 FOLH1 (0.59) DPP7DPP4FOLH1FAPDPP8
SCHEMBL838038 0.82 FOLH1 (0.59) DPP7DPP4FOLH1FAPDPP8
SCHEMBL43812 0.82 FOLH1 (0.59) DPP7DPP4FOLH1FAPDPP8
SCHEMBL14860190 0.81 DPP7 (0.52) DPP7DPP4FOLH1PIN1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
CN-111182880-B WNT compositions and process from serum-free culture conditions 安卡萨再生疗法公司 2024-01-09 CN disclosed
CN-116457034-A Nanomaterial and method of use thereof 康涅狄格大学 2023-07-18 CN disclosed
CN-116445398-A WNT composition and purification method 小利兰斯坦福大学托管委员会 2023-07-18 CN disclosed
EP-4041249-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES The Scripps Research Institute (US) 2022-08-17 EP disclosed
WO-2022170108-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF IN PREVENTION OF RADIATION INJURY AILERON THERAPEUTICS, INC. (US) 2022-08-11 WO disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
EP-3983543-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS The Scripps Research Institute (US) 2022-04-20 EP disclosed
EP-3976635-A1 METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-06 EP disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-114206911-A Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds 加利福尼亚大学董事会 2022-03-18 CN disclosed
CN-114207129-A Agents and methods for replication, transcription and translation in semi-synthetic organisms 斯克利普斯研究所 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed