SCHEMBL29478499

SCHEMBL29478499

c1ccc([C@@H]2NCCc3ccccc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRCP P42785 6/20 1.00
GAA P10253 1/20 0.96
RECQL P46063 1/20 0.74
GID4 Q8IVV7 3/20 0.68
KDM1A O60341 1/20 0.62
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
DRD2 P14416 1/20 0.55
DRD1 P21728 1/20 0.55
SLC22A1 O15245 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL327233 1.00 PRCP (1.00) PRCPGAARECQLGID4KDM1A
SCHEMBL30721685 1.00 PRCP (1.00) PRCPGAARECQLGID4KDM1A
SCHEMBL325083 1.00 PRCP (1.00) PRCPGAARECQLGID4KDM1A
SCHEMBL12046710 1.00 PRCP (1.00) PRCPGAARECQLGID4KDM1A
SCHEMBL1668148 1.00 PRCP (1.00) PRCPGAARECQLGID4KDM1A
SCHEMBL1694774 0.98 PRCP (0.96) PRCPGAARECQLGID4KDM1A
Hydrochloric Acid SCHEMBL1735508 0.98 GAA (1.00) PRCPGAARECQLGID4KDM1A
SCHEMBL1694744 0.98 PRCP (0.96) PRCPGAARECQLGID4KDM1A
SCHEMBL1694844 0.98 PRCP (0.96) PRCPGAARECQLGID4KDM1A
SCHEMBL19610875 0.98 PRCP (0.96) PRCPGAARECQLGID4KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552116-A Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 浙江工业大学 2025-03-04 CN claimed
CN-116102546-B Butyrylcholine esterase and monoamine oxidase B dual inhibitor and application thereof 浙江海洋大学 2025-02-11 CN claimed
CN-116218804-A Imine reductase mutant and method for preparing (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline by reduction thereof 迪嘉药业集团股份有限公司 2023-06-06 CN claimed
CN-116102546-A Butyrylcholine esterase and monoamine oxidase B dual inhibitor and application thereof 浙江海洋大学 2023-05-12 CN claimed
CN-116082232-A Monoamine oxidase inhibitor, preparation method and application thereof 浙江海洋大学 2023-05-09 CN claimed
CN-110407808-B Novel crystal form of (1S) -1-phenyl-3, 4-dihydro-1H-isoquinoline-2-carbonyl imidazole and preparation method thereof 燃点(南京)生物医药科技有限公司 2022-04-15 CN claimed
CN-112142663-B Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 中山奕安泰医药科技有限公司 2022-03-22 CN claimed
CN-119552116-B Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 浙江工业大学 2025-11-11 CN disclosed
CN-119552116-B Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 浙江工业大学 2025-11-11 CN disclosed
CN-119552116-A Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 浙江工业大学 2025-03-04 CN disclosed
CN-119552116-A Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 浙江工业大学 2025-03-04 CN disclosed
CN-119552116-A Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 浙江工业大学 2025-03-04 CN disclosed
CN-116102546-B Butyrylcholine esterase and monoamine oxidase B dual inhibitor and application thereof 浙江海洋大学 2025-02-11 CN disclosed
CN-110352188-B Fluoroallylamine derivatives and use thereof 四川科伦博泰生物医药股份有限公司 2022-11-29 CN disclosed
EP-4077283-A1 PROGRANULIN MODULATORS AND METHODS OF USING THE SAME Arkuda Therapeutics (US) 2022-10-26 EP disclosed
EP-4048677-A1 PROGRANULIN MODULATORS AND METHODS OF USING THE SAME Arkuda Therapeutics (US) 2022-08-31 EP disclosed
CN-110407808-B Novel crystal form of (1S) -1-phenyl-3, 4-dihydro-1H-isoquinoline-2-carbonyl imidazole and preparation method thereof 燃点(南京)生物医药科技有限公司 2022-04-15 CN disclosed
CN-112142663-B Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 中山奕安泰医药科技有限公司 2022-03-22 CN disclosed
CN-112142663-B Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 中山奕安泰医药科技有限公司 2022-03-22 CN disclosed
CN-112142663-B Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline 中山奕安泰医药科技有限公司 2022-03-22 CN disclosed