SCHEMBL29479810

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.62

▸	NPY4R	P50391	8/20	0.62

▸	NPY5R	Q15761	8/20	0.62

▸	NPY1R	P25929	6/20	0.62

▸	CRHR1	P34998	1/20	0.58

▸	CRHR2	Q13324	1/20	0.58

▸	CALCR	P30988	4/20	0.57

▸	RAMP3	O60896	1/20	0.57

▸	EP300	Q09472	1/20	0.56

▸	HIF1A	Q16665	1/20	0.56

▸	GLP1R	P43220	1/20	0.56

▸	GCGR	P47871	1/20	0.56

▸	GIPR	P48546	1/20	0.56

▸	HCRTR1	O43613	1/20	0.55

▸	HCRTR2	O43614	1/20	0.55

▸	NTSR2	O95665	1/20	0.55

▸	NTSR1	P30989	1/20	0.55

▸	F2	P00734	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29479889	0.89	NPY2R (0.67)	NPY2RNPY4RNPY5RNPY1RCRHR1
SCHEMBL29410248	0.89	NPY2R (0.62)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30648466	0.89	CALCR (0.59)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30906423	0.89	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RCRHR1
SCHEMBL30906330	0.89	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RCRHR1
SCHEMBL30906432	0.89	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RCRHR1
SCHEMBL30607381	0.88	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1RCRHR1
SCHEMBL30607406	0.87	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495733	0.87	EP300 (0.66)	NPY2RNPY4RNPY5RNPY1RCRHR1
SCHEMBL30607404	0.87	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RCRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114213534-B	Anti-human PlGF (platelet-derived growth factor) murine monoclonal antibody and application thereof	南京佰抗生物科技有限公司	2022-06-03	—	—	CN	disclosed
CN-114213534-A	Anti-human PlGF (platelet-derived growth factor) mouse-derived monoclonal antibody and application thereof	南京佰抗生物科技有限公司	2022-03-22	—	—	CN	disclosed