Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.50 |
| ▸ | RELA | Q04206 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012083 | 1.00 | NPC1 (0.51) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL28714635 | 0.87 | AGPAT2 (0.49) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL29479743 | 0.83 | KDM4E (0.50) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL23033541 | 0.83 | KDM4E (0.50) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL30782724 | 0.78 | MAPT (0.66) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL30782723 | 0.78 | MAPT (0.66) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL28936032 | 0.77 | AGPAT2 (0.47) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL23012082 | 0.77 | NPC1 (0.43) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL30782721 | 0.76 | PPARG (0.59) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL30782722 | 0.76 | PPARG (0.59) | NPC1RAB9AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |