SCHEMBL29479853

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O

nearest known ligand 0.67

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NPY1R	P25929	1/20	0.65

▸	NPY2R	P49146	1/20	0.65

▸	NPY4R	P50391	1/20	0.65

▸	NPY5R	Q15761	1/20	0.65

▸	CALCR	P30988	3/20	0.61

▸	GLP1R	P43220	10/20	0.61

▸	KEAP1	Q14145	1/20	0.60

▸	CXCL8	P10145	2/20	0.60

▸	CCKBR	P32239	1/20	0.59

▸	CRHR1	P34998	1/20	0.59

▸	CRHR2	Q13324	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906385	0.91	NPY2R (0.71)	NPY1RNPY2RNPY4RNPY5RCALCR
SCHEMBL31182837	0.90	CXCR4 (0.67)	NPY1RNPY2RNPY4RNPY5RCALCR
SCHEMBL30431894	0.90	NPY1R (0.62)	NPY1RNPY2RNPY4RNPY5RCALCR
SCHEMBL30906422	0.90	NPY1R (0.68)	NPY1RNPY2RNPY4RNPY5RCALCR
SCHEMBL30906368	0.89	NPY2R (0.65)	NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30906461	0.89	NPY1R (0.68)	NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29679514	0.89	NPY1R (0.68)	NPY1RNPY2RNPY4RNPY5RCALCR
SCHEMBL31182892	0.89	CALCR (0.66)	NPY1RNPY2RNPY4RNPY5RCALCR
SCHEMBL30658315	0.89	NPY1R (0.68)	NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30648474	0.88	NPY1R (0.66)	NPY1RNPY2RNPY4RNPY5RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114213534-B	Anti-human PlGF (platelet-derived growth factor) murine monoclonal antibody and application thereof	南京佰抗生物科技有限公司	2022-06-03	—	—	CN	disclosed
CN-114213534-A	Anti-human PlGF (platelet-derived growth factor) mouse-derived monoclonal antibody and application thereof	南京佰抗生物科技有限公司	2022-03-22	—	—	CN	disclosed