Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480515 | 0.87 | ADORA2A (0.37) | ADORA2AADORA2BADORA1EGLN1EPHX2 | |
| SCHEMBL29480540 | 0.85 | ADORA2A (0.37) | ADORA2AADORA2BADORA1EPHX2GRM4 | |
| SCHEMBL29480530 | 0.84 | ADORA2A (0.34) | ADORA2AADORA2BADORA1EPHX2GRM4 | |
| SCHEMBL29480620 | 0.83 | ADORA2A (0.36) | ADORA2AADORA2BADORA1GCG | |
| SCHEMBL29480567 | 0.82 | ADORA2A (0.35) | ADORA2AADORA2BADORA1GCG | |
| SCHEMBL29480561 | 0.82 | ADORA2A (0.35) | ADORA2AADORA2BADORA1GCG | |
| SCHEMBL29480590 | 0.82 | ADORA2A (0.35) | ADORA2AADORA2BADORA1GCG | |
| SCHEMBL29480548 | 0.82 | ADORA2A (0.38) | ADORA2AADORA2BADORA1EGLN1EPHX2 | |
| SCHEMBL29480501 | 0.81 | ADORA2A (0.33) | ADORA2AADORA2BADORA1EGLN1EPHX2 | |
| SCHEMBL29480538 | 0.81 | ADORA2A (0.34) | ADORA2AADORA2BADORA1EGLN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |