Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22736011 | 0.87 | GRM4 (0.35) | GRM4 | |
| SCHEMBL29480656 | 0.87 | GRM4 (0.35) | GRM4 | |
| SCHEMBL22736187 | 0.85 | GRM4 (0.34) | GRM4 | |
| SCHEMBL29568178 | 0.85 | GRM4 (0.34) | GRM4 | |
| SCHEMBL29567531 | 0.84 | GRM4 (0.32) | GRM4 | |
| SCHEMBL22716906 | 0.84 | GRM4 (0.32) | GRM4 | |
| SCHEMBL22735745 | 0.83 | GRM4 (0.34) | GCGGRM4 | |
| SCHEMBL22735739 | 0.83 | GRM4 (0.34) | GCGGRM4 | |
| SCHEMBL29567619 | 0.83 | GRM4 (0.34) | GCGGRM4 | |
| SCHEMBL29480558 | 0.83 | GRM4 (0.34) | GCGGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |