Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | PKM | P14618 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424543 | 1.00 | KMT2A (0.58) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL22581386 | 1.00 | KMT2A (0.58) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL29424541 | 1.00 | KMT2A (0.58) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL1700350 | 1.00 | KMT2A (0.58) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL22581236 | 1.00 | KMT2A (0.58) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL25417524 | 0.90 | KMT2A (0.56) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL1700027 | 0.90 | KMT2A (0.58) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL25416070 | 0.88 | KMT2A (0.56) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL28845370 | 0.88 | MAPT (0.56) | KMT2AMEN1MAPTPKMPOLB | |
| SCHEMBL1700354 | 0.87 | MAPT (0.54) | KMT2AMEN1MAPTPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084904-A | Benzamide compounds | 里科瑞尔姆IP控股有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-111801327-B | Benzamide compounds | 里科瑞尔姆IP控股有限责任公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114126616-A | Nanoparticle formulations of BCL-2 inhibitors | 里科瑞尔姆IP控股有限责任公司 | 2022-03-01 | — | — | CN | disclosed |