Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.55 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.55 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029475 | 1.00 | ITGAV (0.59) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22029492 | 0.92 | ITGAV (0.66) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22029432 | 0.92 | ITGAV (0.66) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22029430 | 0.92 | ITGAV (0.66) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22029483 | 0.91 | ITGAV (0.59) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL24363074 | 0.84 | ITGAV (0.50) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL24363100 | 0.83 | ITGAV (0.51) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22029438 | 0.83 | ITGAV (0.78) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22073480 | 0.83 | ITGAV (0.78) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22074099 | 0.83 | ITGAV (0.78) | ITGAVITGB3ITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481814-B1 | TETRAHYDRONAPHTHYRIDINEPENTANAMIDE INTEGRIN ANTAGONISTS | UNIV ROCKEFELLER (US) | 2022-04-27 | — | — | EP | disclosed |