Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.68 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.68 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.58 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.56 |
| ▸ | ITGB8 | P26012 | 8/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029442 | 1.00 | ITGAV (0.68) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24193794 | 0.91 | ITGAV (0.66) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029437 | 0.90 | ITGAV (0.69) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL21706034 | 0.90 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029478 | 0.90 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL29813942 | 0.88 | ITGAV (0.61) | ITGAVITGB3ITGB6 | |
| SCHEMBL24683292 | 0.88 | ITGAV (0.61) | ITGAVITGB3ITGB6 | |
| SCHEMBL21852990 | 0.88 | ITGAV (0.61) | ITGAVITGB3ITGB6 | |
| SCHEMBL21852991 | 0.88 | ITGAV (0.61) | ITGAVITGB3ITGB6 | |
| SCHEMBL29813809 | 0.88 | ITGAV (0.61) | ITGAVITGB3ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481814-B1 | TETRAHYDRONAPHTHYRIDINEPENTANAMIDE INTEGRIN ANTAGONISTS | UNIV ROCKEFELLER (US) | 2022-04-27 | — | — | EP | disclosed |