Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.75 |
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232327 | 0.87 | TAAR1 (1.00) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10897947 | 0.84 | TAAR1 (0.95) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1924679 | 0.84 | TAAR1 (0.95) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Bromide SCHEMBL28684127 | 0.84 | TAAR1 (0.95) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Iodide SCHEMBL29127481 | 0.84 | TAAR1 (0.95) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| SCHEMBL9468426 | 0.80 | TAAR1 (0.86) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Phenethylamine SCHEMBL27697034 | 0.78 | HTR2A (0.73) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29484054 | 0.77 | TAAR1 (0.64) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29484053 | 0.77 | TAAR1 (0.64) | TAAR1MAOBHTR3AKDM4EALDH1A1 | |
| SCHEMBL8351927 | 0.77 | TAAR1 (0.78) | TAAR1MAOBHTR3AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612429-B2 | Derivatives of dolaproine-dolaisoleuine peptides | AGENSYS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-20220204557-A1 | DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES | AGENSYS, INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-11312748-B2 | Derivatives of dolaproine-dolaisoleucine peptides | AGENSYS, INC. (US) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204557-A1 | DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES | DDOST, VIP, THPO | TAAR1 4857/4885MAOB 4627/4885HTR3A 4487/4885 |
| US-12612429-B2 | Derivatives of dolaproine-dolaisoleuine peptides | DDOST, NGLY1, GRPR | TAAR1 3642/4885MAOB 4617/4885HTR3A 4459/4885 |
| US-11312748-B2 | Derivatives of dolaproine-dolaisoleucine peptides | VIP, DDOST, DNPEP | TAAR1 4668/4885MAOB 4737/4885HTR3A 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.