Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812101 | 0.83 | SMN1; SMN2 (0.64) | ALOX12SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL30223355 | 0.83 | SMN1; SMN2 (0.64) | ALOX12SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL30223215 | 0.83 | SMN1; SMN2 (0.64) | ALOX12SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL1962256 | 0.80 | KMT2A (0.60) | ALDH1A1ALOX12SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL3130690 | 0.80 | KMT2A (0.60) | ALDH1A1ALOX12SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL24575950 | 0.76 | HPGD (0.72) | ALOX12SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL5674448 | 0.76 | SMN1; SMN2 (0.68) | ALOX12SMN1; SMN2KMT2ACYP2C9CYP2C19 | |
| SCHEMBL13973608 | 0.76 | KMT2A (0.64) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL10341246 | 0.74 | KMT2A (0.62) | ALDH1A1ALOX12GLASMN1; SMN2RAB9A | |
| SCHEMBL4420466 | 0.74 | SMN1; SMN2 (0.66) | ALDH1A1ALOX12SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |