Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.50 |
| ▸ | MET | P08581 | 10/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 3/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22960033 | 1.00 | KDR (0.50) | KDRPDGFRAMETIGF1RFGFR2 | |
| SCHEMBL29487188 | 0.91 | PDGFRA (0.59) | KDRPDGFRAMETFGFR2AXL | |
| SCHEMBL174159 | 0.91 | PDGFRA (0.59) | KDRPDGFRAMETFGFR2AXL | |
| SCHEMBL31393028 | 0.88 | PDGFRA (0.48) | KDRPDGFRAMETIGF1RFGFR2 | |
| SCHEMBL13936618 | 0.87 | PDGFRA (0.52) | KDRPDGFRAMETFGFR2AXL | |
| SCHEMBL14966986 | 0.87 | PDGFRA (0.59) | KDRPDGFRAPDGFRBAMY1A | |
| SCHEMBL1133098 | 0.87 | AXL (0.59) | KDRPDGFRAMETAXLMERTK | |
| SCHEMBL1133096 | 0.87 | AXL (0.59) | KDRPDGFRAMETAXLMERTK | |
| SCHEMBL20032552 | 0.86 | PDGFRA (0.51) | KDRPDGFRAMETIGF1RFGFR2 | |
| SCHEMBL22009936 | 0.85 | PDGFRA (0.56) | KDRPDGFRAMETFGFR2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206883-A | Oxopyridine fused ring derivative and pharmaceutical composition comprising the same | 伟迈可生物有限公司 | 2022-03-18 | — | — | CN | disclosed |