Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.66 |
| ▸ | KDR | P35968 | 2/20 | 0.66 |
| ▸ | BRAF | P15056 | 1/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.65 |
| ▸ | BTK | Q06187 | 5/20 | 0.65 |
| ▸ | JAK3 | P52333 | 3/20 | 0.65 |
| ▸ | KIT | P10721 | 2/20 | 0.65 |
| ▸ | SRC | P12931 | 2/20 | 0.65 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.65 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.65 |
| ▸ | ITK | Q08881 | 2/20 | 0.65 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.65 |
| ▸ | CIT | O14578 | 1/20 | 0.65 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.65 |
| ▸ | GAK | O14976 | 1/20 | 0.65 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.65 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.65 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.65 |
| ▸ | STK17B | O94768 | 1/20 | 0.65 |
| ▸ | STK10 | O94804 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452115 | 1.00 | EGFR (0.66) | EGFRKDRBRAFERBB2BTK | |
| SCHEMBL27727371 | 0.84 | EGFR (0.65) | EGFRKDRBRAFERBB2BTK | |
| SCHEMBL14127461 | 0.81 | EGFR (0.45) | EGFRKDRBRAFERBB2BTK | |
| SCHEMBL1151056 | 0.81 | EGFR (0.82) | EGFRKDRBRAFERBB2BTK | |
| Hydrochloric Acid SCHEMBL15565027 | 0.80 | EGFR (0.81) | EGFRKDRBRAFERBB2BTK | |
| SCHEMBL12694361 | 0.79 | EGFR (1.00) | EGFRKDRBRAFERBB2BTK | |
| SCHEMBL5040071 | 0.79 | EGFR (0.61) | EGFRKDRBRAFERBB2BTK | |
| SCHEMBL3520111 | 0.79 | EGFR (0.72) | EGFRKDRERBB2BTKJAK3 | |
| Canertinib SCHEMBL29655741 | 0.79 | EGFR (1.00) | EGFRKDRERBB2BTKJAK3 | |
| Canertinib SCHEMBL29368458 | 0.79 | EGFR (1.00) | EGFRKDRERBB2BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630416-A1 | CANCER TREATING COMPOUNDS | University of Bradford (GB) | 2025-10-15 | — | — | EP | disclosed |
| CN-114286711-A | Bicyclic heterocyclic compounds as inhibitors of BCDIN3D activity | 风暴治疗有限公司 | 2022-04-05 | — | — | CN | disclosed |