Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2505519 | 1.00 | HTR2C (0.40) | HTR2CHTR2BESR2CXCR2DDB1 | |
| SCHEMBL8724510 | 0.90 | HCRTR2 (0.37) | HTR2CHTR2BCXCR2DDB1CRBN | |
| SCHEMBL20011092 | 0.87 | ESR2 (0.40) | ESR2CXCR2DDB1CRBNTP53 | |
| SCHEMBL6953228 | 0.85 | HCAR2 (0.43) | HTR2CHTR2BESR2HTR1ASLC6A2 | |
| SCHEMBL12477783 | 0.84 | HTR2C (0.47) | HTR2CHTR2BHCRTR2HTR1ASLC6A2 | |
| SCHEMBL428500 | 0.81 | TP53 (0.43) | HTR2CHTR2BTP53CHRNB2CHRNA4 | |
| SCHEMBL829168 | 0.80 | CALCRL (0.38) | HTR2CHTR2BCXCR2DDB1CRBN | |
| SCHEMBL28247605 | 0.80 | HTR2C (0.44) | HTR2CHTR2BTP53HCRTR2HTR1A | |
| SCHEMBL13293459 | 0.80 | CXCR2 (0.37) | HTR2CHTR2BCXCR2TP53HCRTR2 | |
| SCHEMBL28254585 | 0.79 | ABCB1 (0.46) | HTR2CHTR2BESR2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |