Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.58 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.51 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.48 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685559 | 1.00 | CRBN (0.58) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685705 | 0.89 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL1413650 | 0.87 | CRBN (0.71) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685481 | 0.87 | CRBN (0.60) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685757 | 0.87 | CRBN (0.59) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL29488352 | 0.87 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685560 | 0.87 | CRBN (0.69) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685786 | 0.87 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685712 | 0.86 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685780 | 0.86 | CRBN (0.63) | CRBNDDB1GSPT1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | claimed |
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | claimed |
| EP-3976623-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2022-04-06 | — | — | EP | claimed |
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3976623-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |