Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.60 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685561 | 1.00 | CRBN (0.60) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685705 | 0.91 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685811 | 0.90 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL29488375 | 0.90 | CRBN (0.64) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL29488387 | 0.89 | CRBN (0.63) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685780 | 0.89 | CRBN (0.63) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685497 | 0.88 | CRBN (0.57) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL29488400 | 0.88 | CRBN (0.60) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL22685663 | 0.88 | CRBN (0.60) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL29488351 | 0.88 | CRBN (0.57) | CRBNDDB1GSPT1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | claimed |
| EP-3976623-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2022-04-06 | — | — | EP | claimed |
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| EP-3976623-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |