Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306069 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1306064 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1306173 | 0.91 | KDM4E (0.45) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1306168 | 0.91 | KDM4E (0.45) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1307236 | 0.91 | CNR2 (0.41) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1307234 | 0.91 | CNR2 (0.41) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1306229 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1306233 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1306235 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| Cg-200745 SCHEMBL29352975 | 0.85 | HTR1B (0.44) | KDM4EALDH1A1HPGDTDP1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | claimed |
| CN-112930177-B | Pharmaceutical compositions containing alkylcarbamoyl naphthoyl octenoyl hydroxyamide phosphate, tartrate or combinations thereof and methods of making the same | 晶体基因技术株式会社 | 2024-01-30 | — | — | CN | disclosed |
| EP-4155292-A1 | METHOD FOR PRODUCING PHARMACEUTICALLY ACCEPTABLE SALT OF ALKYLCARBAMOYL NAPHTHALENYLOXY OCTENOYLHYDROXYAMIDE | Crystalgenomics, Inc. (KR) | 2023-03-29 | — | — | EP | disclosed |
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | disclosed |
| CN-110740989-B | Pharmaceutically acceptable salts of alkylcarbamoylnaphthoxyoctenoylhydroxyamides or derivatives thereof and process for preparing the same | 晶体基因技术株式会社 | 2022-03-08 | — | — | CN | disclosed |