Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305360 | 1.00 | GAA (0.45) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1305354 | 1.00 | GAA (0.45) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1308416 | 0.91 | HPGD (0.46) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1308420 | 0.91 | HPGD (0.46) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1305938 | 0.90 | GAA (0.47) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1305937 | 0.90 | GAA (0.47) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1306560 | 0.85 | CYP1A2 (0.46) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1306554 | 0.85 | CYP1A2 (0.46) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1305788 | 0.84 | HPGD (0.49) | GAAPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1305785 | 0.84 | HPGD (0.49) | GAAPOLBCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | claimed |
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | disclosed |
| CN-110740989-B | Pharmaceutically acceptable salts of alkylcarbamoylnaphthoxyoctenoylhydroxyamides or derivatives thereof and process for preparing the same | 晶体基因技术株式会社 | 2022-03-08 | — | — | CN | disclosed |