Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30528347 | 1.00 | KDM4E (0.30) | KDM4EALDH1A1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL29102821 | 1.00 | KDM4E (0.30) | KDM4EALDH1A1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL24386901 | 1.00 | KDM4E (0.30) | KDM4EALDH1A1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL29102819 | 1.00 | KDM4E (0.30) | KDM4EALDH1A1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL16972297 | 0.82 | KDM4E (0.30) | KDM4EALOX15L3MBTL1 | |
| SCHEMBL614267 | 0.82 | KDM4E (0.30) | KDM4EALOX15L3MBTL1 | |
| SCHEMBL614268 | 0.82 | KDM4E (0.30) | KDM4EALOX15L3MBTL1 | |
| SCHEMBL24529378 | 0.82 | KDM4E (0.30) | KDM4EALOX15L3MBTL1 | |
| SCHEMBL614269 | 0.82 | KDM4E (0.30) | KDM4EALOX15L3MBTL1 | |
| SCHEMBL30271817 | 0.82 | KDM4E (0.30) | KDM4EALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232425-A1 | CTPS1 INHIBITORS AND USES THEREOF | Nimbus Clotho, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |