Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828595 | 0.79 | ACE (0.61) | ACESLC7A5MME | |
| SCHEMBL21828594 | 0.79 | ACE (0.61) | ACESLC7A5MME | |
| SCHEMBL11459948 | 0.77 | SLC7A5 (0.52) | SLC7A5LARS1 | |
| SCHEMBL11459947 | 0.77 | SLC7A5 (0.52) | SLC7A5LARS1 | |
| SCHEMBL14671217 | 0.76 | KDM4E (0.56) | ACE | |
| SCHEMBL30534373 | 0.76 | KDM4E (0.56) | ACE | |
| SCHEMBL2840621 | 0.76 | FCER2 (0.44) | ACESLC7A5LARS1MMEFCER2 | |
| SCHEMBL30288000 | 0.76 | ACE (0.56) | ACESLC7A5MME | |
| SCHEMBL31720932 | 0.76 | ACE (0.51) | ACESLC7A5MME | |
| SCHEMBL30311049 | 0.76 | ACE (0.56) | ACESLC7A5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428804-B | Immunomodulator | 百时美施贵宝公司 | 2022-06-28 | — | — | CN | disclosed |
| EP-3271373-B1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2022-03-16 | — | — | EP | disclosed |