Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.50 |
| ▸ | KDR | P35968 | 9/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.46 |
| ▸ | KRAS | P01116 | 7/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862964 | 1.00 | EGFR (0.50) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL22862653 | 0.88 | EGFR (0.44) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL29490224 | 0.88 | EGFR (0.44) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL22862686 | 0.87 | EGFR (0.50) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL29490225 | 0.87 | EGFR (0.50) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL22862609 | 0.86 | SOS1 (0.59) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL29490269 | 0.86 | SOS1 (0.59) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL29490218 | 0.83 | EGFR (0.49) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL22862684 | 0.83 | EGFR (0.49) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL22862732 | 0.81 | EGFR (0.44) | EGFRKDRPDGFRBSOS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |