Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 17/20 | 0.44 |
| ▸ | KRAS | P01116 | 8/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862607 | 1.00 | SOS1 (0.44) | SOS1KRASIDO1EGFRCTNNB1 | |
| SCHEMBL24704140 | 1.00 | SOS1 (0.44) | SOS1KRASIDO1EGFRCTNNB1 | |
| SCHEMBL22862729 | 0.83 | CA1 (0.38) | SOS1KRASIDO1EGFR | |
| SCHEMBL22862674 | 0.82 | NPC1 (0.43) | SOS1IDO1 | |
| SCHEMBL22862939 | 0.82 | NPC1 (0.43) | SOS1IDO1 | |
| SCHEMBL22862811 | 0.81 | EGFR (0.39) | SOS1EGFR | |
| SCHEMBL22862431 | 0.81 | EGFR (0.39) | SOS1EGFR | |
| SCHEMBL29490298 | 0.81 | EGFR (0.39) | SOS1EGFR | |
| SCHEMBL22862681 | 0.80 | NPC1 (0.44) | SOS1IDO1 | |
| SCHEMBL24704141 | 0.80 | NPC1 (0.44) | SOS1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |